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The structural basis of urea-induced protein unfolding in β-catenin
Although urea and guanidine hydrochloride are commonly used to denature proteins, the molecular underpinnings of this process have remained unclear for a century. To address this question, crystal structures of β-catenin were determined at various urea concentrations. These structures contained at l...
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| 出版年: | Acta Crystallogr D Biol Crystallogr |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Union of Crystallography
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220971/ https://ncbi.nlm.nih.gov/pubmed/25372676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714018094 |
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