Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival

BACKGROUND: Genetic BRCA2 insufficiency is associated with breast cancer development; however, in sporadic breast cancer cases, high BRCA2 expression is paradoxically correlated with poor prognosis. Because DSS1, a mammalian component of the transcription/RNA export complex, is known to stabilize BR...

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Udgivet i:BMC Cancer
Main Authors: Rezano, Andri, Kuwahara, Kazuhiko, Yamamoto-Ibusuki, Mutsuko, Kitabatake, Masahiro, Moolthiya, Penpak, Phimsen, Suchada, Suda, Taiji, Tone, Shigenobu, Yamamoto, Yutaka, Iwase, Hirotaka, Sakaguchi, Nobuo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219476/
https://ncbi.nlm.nih.gov/pubmed/24289229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-562
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