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Evolutionary profiling reveals the heterogeneous origins of classes of human disease genes: implications for modeling disease genetics in animals

BACKGROUND: The recent expansion of whole-genome sequence data available from diverse animal lineages provides an opportunity to investigate the evolutionary origins of specific classes of human disease genes. Previous studies have observed that human disease genes are of particularly ancient origin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Evol Biol
Egile Nagusiak: Maxwell, Evan K, Schnitzler, Christine E, Havlak, Paul, Putnam, Nicholas H, Nguyen, Anh-Dao, Moreland, R Travis, Baxevanis, Andreas D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219131/
https://ncbi.nlm.nih.gov/pubmed/25281000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-014-0212-1
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