Evolutionary profiling reveals the heterogeneous origins of classes of human disease genes: implications for modeling disease genetics in animals

BACKGROUND: The recent expansion of whole-genome sequence data available from diverse animal lineages provides an opportunity to investigate the evolutionary origins of specific classes of human disease genes. Previous studies have observed that human disease genes are of particularly ancient origin...

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Veröffentlicht in:BMC Evol Biol
Hauptverfasser: Maxwell, Evan K, Schnitzler, Christine E, Havlak, Paul, Putnam, Nicholas H, Nguyen, Anh-Dao, Moreland, R Travis, Baxevanis, Andreas D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219131/
https://ncbi.nlm.nih.gov/pubmed/25281000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-014-0212-1
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