CS-29 A KINOME-WIDE RNAi-SCREEN IN DROSOPHILA GLIA AND HUMAN GBM CELLS REVEALS THAT Stk17A DRIVES NEOPLASTIC GLIAL CELL PROLIFERATION AND INVASION

Glioblastomas (GBM), the most common primary malignant brain tumors, are highly proliferative and diffusely invasive, and are incurable with current therapies. Genetic and molecular analyses reveal that GBMs frequently harbor mutations that activate the EGFR receptor tyrosine kinase (EGFR) and Pi-3...

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Main Authors: Read, Renee, Marquez, Jhomar, Mosley, Colleen
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217986/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.29
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