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Speckle-type POZ protein mutations interrupt tumor suppressor function of speckle-type POZ protein in prostate cancer by affecting androgen receptor degradation

Large scale exome sequencing studies have revealed regions of the genome, which contribute to the castrate resistant prostate cancer (CRPC) phenotype.123 Such studies have identified mutations in genes, which may have diagnostic/prognostic potential, or which may be targeted therapeutically. Two of...

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Hlavní autoři: Lai, John, Batra, Jyotsna
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215653/
https://ncbi.nlm.nih.gov/pubmed/24969063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.133323
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