Acetylcholine Receptor (AChR) Clustering Is Regulated Both by Glycogen Synthase Kinase 3β (GSK3β)-dependent Phosphorylation and the Level of CLIP-associated Protein 2 (CLASP2) Mediating the Capture of Microtubule Plus-ends

The postsynaptic apparatus of the neuromuscular junction (NMJ) traps and anchors acetylcholine receptors (AChRs) at high density at the synapse. We have previously shown that microtubule (MT) capture by CLASP2, a MT plus-end-tracking protein (+TIP), increases the size and receptor density of AChR cl...

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Detalhes bibliográficos
Main Authors: Basu, Sreya, Sladecek, Stefan, Pemble, Hayley, Wittmann, Torsten, Slotman, Johan A., van Cappellen, Wiggert, Brenner, Hans-Rudolf, Galjart, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215261/
https://ncbi.nlm.nih.gov/pubmed/25231989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589457
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