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Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.
One of the more intriguing aspects of transforming growth factor beta 1 (TGF beta 1) is its ability to function as both a mitogenic factor for certain mesenchymal cells and a potent growth inhibitor of lymphoid, endothelial, and epithelial cells. Data are presented indicating that c-myc may play a p...
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Hlavní autoři: | , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
1995
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC42141/ https://ncbi.nlm.nih.gov/pubmed/7724545 |
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