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The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions

Barrier characteristics of brain endothelial cells forming the blood–brain barrier (BBB) are tightly regulated by cellular and acellular components of the neurovascular unit. During embryogenesis, the accumulation of the heparan sulfate proteoglycan agrin in the basement membranes ensheathing brain...

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Main Authors: Steiner, Esther, Enzmann, Gaby U., Lyck, Ruth, Lin, Shuo, Rüegg, Markus A., Kröger, Stephan, Engelhardt, Britta
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210653/
https://ncbi.nlm.nih.gov/pubmed/25107608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-014-1969-7
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