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Intermittent dosing with vemurafenib in BRAF V600E-mutant melanoma: review of a case series

The selective BRAF inhibitors, vemurafenib and dabrafenib, yield high response rates and improved overall survival in patients with BRAF V600E-mutant metastatic melanoma. Acquired drug resistance and drug toxicity are key challenges when using these drugs. We investigated whether vemurafenib toxicit...

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Bibliografiske detaljer
Main Authors: Dooley, Andrew J., Gupta, Avinash, Bhattacharyya, Madhumita, Middleton, Mark R.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206651/
https://ncbi.nlm.nih.gov/pubmed/25364391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834014548187
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