Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats

BACKGROUND: Despite high prevalence of anxiety accompanying with chronic pain, the mechanisms underlying pain-related anxiety are largely unknown. With its well-documented role in pain and emotion processing, the amygdala may act as a key player in pathogenesis of neuropathic pain-related anxiety. P...

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Main Authors: Jiang, Hong, Fang, Dong, Kong, Ling-Yu, Jin, Zi-Run, Cai, Jie, Kang, Xue-Jing, Wan, You, Xing, Guo-Gang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201706/
https://ncbi.nlm.nih.gov/pubmed/25277376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0072-z
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