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Modeling time-dependent transcription effects of HER2 oncogene and discovery of a role for E2F2 in breast cancer cell-matrix adhesion

Motivation: Oncogenes are known drivers of cancer phenotypes and targets of molecular therapies; however, the complex and diverse signaling mechanisms regulated by oncogenes and potential routes to targeted therapy resistance remain to be fully understood. To this end, we present an approach to infe...

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Hlavní autoři: Bollig-Fischer, Aliccia, Marchetti, Luca, Mitrea, Cristina, Wu, Jiusheng, Kruger, Adéle, Manca, Vincenzo, Drăghici, Sorin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201152/
https://ncbi.nlm.nih.gov/pubmed/25028721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu400
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