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Recombination between Palindromes P5 and P1 on the Human Y Chromosome Causes Massive Deletions and Spermatogenic Failure

It is widely believed that at least three nonoverlapping regions of the human Y chromosome—AZFa, AZFb, and AZFc (“azoospermia factors” a, b, and c)—are essential for normal spermatogenesis. These intervals are defined by interstitial Y-chromosome deletions that impair or extinguish spermatogenesis....

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Autors principals: Repping, Sjoerd, Skaletsky, Helen, Lange, Julian, Silber, Sherman, van der Veen, Fulco, Oates, Robert D., Page, David C., Rozen, Steve
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC419997/
https://ncbi.nlm.nih.gov/pubmed/12297986
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