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The T-box gene family: emerging roles in development, stem cells and cancer
The T-box family of transcription factors exhibits widespread involvement throughout development in all metazoans. T-box proteins are characterized by a DNA-binding motif known as the T-domain that binds DNA in a sequence-specific manner. In humans, mutations in many of the genes within the T-box fa...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists
2014
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197708/ https://ncbi.nlm.nih.gov/pubmed/25294936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.104471 |
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