HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

Dendritic cells (DCs) undergo maturation during virus infection and thereby become potent stimulators of cell-mediated immunity. HIV-1 replicates in immature DCs, but we now find that infection is not accompanied by many components of maturation in either infected cells or uninfected bystanders. The...

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Bibliographic Details
Main Authors: Granelli-Piperno, Angela, Golebiowska, Angelika, Trumpfheller, Christine, Siegal, Frederick P., Steinman, Ralph M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC419664/
https://ncbi.nlm.nih.gov/pubmed/15128934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402431101
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