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Solution structure of a nitrous acid induced DNA interstrand cross-link

Nitrous acid is a mutagenic agent. It can induce interstrand cross-links in duplex DNA, preferentially at d(CpG) steps: two guanines on opposite strands are linked via a single shared exocyclic imino group. Recent synthetic advances have led to the production of large quantities of such structurally...

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Detalhes bibliográficos
Main Authors: Edfeldt, N. B. Fredrik, Harwood, Eric A., Sigurdsson, Snorri Th., Hopkins, Paul B., Reid, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419607/
https://ncbi.nlm.nih.gov/pubmed/15155847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh606
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