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From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs)

Our understanding of the molecular mechanisms underlying the pharmacological actions of estrogen receptor (ER) ligands has evolved considerably in recent years. Much of this knowledge has come from a detailed dissection of the mechanism(s) of action of the Selective Estrogen Receptor Modulators (SER...

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Detalhes bibliográficos
Main Authors: Wardell, Suzanne E., Nelson, Erik R., McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192009/
https://ncbi.nlm.nih.gov/pubmed/25084324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.07.013
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