From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs)

Documenti analoghi

• The Molecular Mechanisms Underlying the Pharmacological Actions of Estrogens, SERMs and Oxysterols: Implications for the Treatment and Prevention of Osteoporosis
  di: Nelson, Erik R., et al.
  Pubblicazione: (2012)
• The Discovery and Development of Selective Estrogen Receptor Modulators (SERMs) for Clinical Practice
  di: Maximov, Philipp Y, et al.
  Pubblicazione: (2013)
• Research Resource: Transcriptional Profiling in a Cellular Model of Breast Cancer Reveals Functional and Mechanistic Differences Between Clinically Relevant SERM and Between SERM/Estrogen Complexes
  di: Wardell, Suzanne E., et al.
  Pubblicazione: (2012)
• Bioactivation of Selective Estrogen Receptor Modulators (SERMs)
  di: Dowers, Tamara S., et al.
  Pubblicazione: (2006)
• The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy
  di: Wardell, Suzanne E., et al.
  Pubblicazione: (2011)