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Quantification of plasma HIV RNA using chemically-engineered peptide nucleic acids

The remarkable stability of peptide nucleic acids (PNAs) toward enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of chemically-engineered PNAs for the quantitative detection of HIV RNA at clinically relevant levels th...

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Autors principals: Zhao, Chao, Hoppe, Travis, Setty, Mohan Kumar Haleyur Giri, Murray, Danielle, Chun, Tae-Wook, Hewlett, Indira, Appella, Daniel H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187110/
https://ncbi.nlm.nih.gov/pubmed/25283173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6079
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