Inhibition of the NLRP3 inflammasome reduces the severity of experimentally-induced acute pancreatitis in obese mice

Acute pancreatitis (AP), while most often a mild and self-limiting inflammatory disease, worsens to a characteristically necrotic severe acute pancreatitis (SAP) in about 20% of cases. Obesity, affecting more than a third of American adults, is a risk factor for the development of SAP, but the exact...

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Bibliographic Details
Main Authors:	York, Jason M, Castellanos, Karla J, Cabay, Robert J, Fantuzzi, Giamila
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4180798/ https://ncbi.nlm.nih.gov/pubmed/25152324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2014.06.012
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Inhibition of the NLRP3 inflammasome reduces the severity of experimentally-induced acute pancreatitis in obese mice

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