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When noise makes music: HIV reactivation with transcriptional noise enhancers

Reactivating latent HIV is key to depleting the virus reservoir in AIDS patients. A recent paper has described the rationale for and discovery of a new class of drugs - transcriptional noise enhancers - that can synergize with conventional transcription activators to more effectively reactivate late...

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Библиографические подробности
Главные авторы: Tan, Xu, Elledge, Stephen J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179226/
https://ncbi.nlm.nih.gov/pubmed/25276233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0055-9
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