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Epstein-Barr Virus EBNA1 Protein Regulates Viral Latency through Effects on let-7 MicroRNA and Dicer

The EBNA1 protein of Epstein-Barr virus (EBV) plays multiple roles in EBV latent infection, including altering cellular pathways relevant for cancer. Here we used microRNA (miRNA) cloning coupled with high-throughput sequencing to identify the effects of EBNA1 on cellular miRNAs in two nasopharyngea...

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Détails bibliographiques
Auteurs principaux: Mansouri, Sheila, Pan, Qun, Blencowe, Benjamin J., Claycomb, Julie M., Frappier, Lori
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178782/
https://ncbi.nlm.nih.gov/pubmed/25031339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01785-14
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