Novel heparan sulfate assay by using automated high-throughput mass spectrometry: application to monitoring and screening for mucopolysaccharidoses

Mucopolysaccharidoses (MPS) are caused by deficiency of one of a group of specific lysosomal enzymes, resulting in excessive accumulation of glycosaminoglycans (GAGs). We previously developed GAG assay methods using liquid chromatography tandem mass spectrometry (LC-MS/MS); however, it takes 4–5 min...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shimada, Tsutomu, Kelly, Joan, LaMarr, William A, van Vlies, Naomi, Yasuda, Eriko, Mason, Robert W., Mackenzie, William, Kubaski, Francyne, Giugliani, Roberto, Chinen, Yasutsugu, Yamaguchi, Seiji, Suzuki, Yasuyuki, Orii, Kenji E., Fukao, Toshiyuki, Orii, Tadao, Tomatsu, Shunji
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177953/
https://ncbi.nlm.nih.gov/pubmed/25092413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.07.008
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