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Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A(2), cyclooxygenases, lipoxygenase and pro-inflammatory cytokines
Arachidonic acid metabolism leads to the generation of key lipid mediators which play a fundamental role during inflammation. The inhibition of enzymes involved in arachidonic acid metabolism has been considered as a synergistic anti-inflammatory effect with enhanced spectrum of activity. A series o...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172049/ https://ncbi.nlm.nih.gov/pubmed/25258510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S67370 |
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