Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells

Thyroid hormone (3,5,3′-triiodothyronine, T3; L-thyroxine, T4) enhances cancer cell proliferation, invasion and angiogenesis via a discrete receptor located near the RGD recognition site on αvβ3 integrin. Tetraiodothyroacetic acid (tetrac) and its nanoparticulate formulation interfere with binding o...

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Bibliografske podrobnosti
Main Authors: Cohen, Keren, Flint, Nir, Shalev, Shachar, Erez, Daniel, Baharal, Tal, Davis, Paul J., Hercbergs, Aleck, Ellis, Martin, Ashur-Fabian, Osnat
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171632/
https://ncbi.nlm.nih.gov/pubmed/25071016
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