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Acquisition of radioresistance in docetaxel-resistant human lung adenocarcinoma cells is linked with dysregulation of miR-451/c-Myc-survivin/rad-51 signaling

Chemoresistant tumors usually fail to respond to radiotherapy. However, the mechanisms involved in chemo- and radiotherapy cross resistance are not fully understood. Previously, we have identified microRNA (miR)-451 as a tumor suppressor in lung adenocarcinoma (LAD). However, whether miR-451 plays c...

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Bibliografiske detaljer
Main Authors: Wang, Rui, Chen, Dong-Qin, Huang, Jia-Yuan, Zhang, Kai, Feng, Bing, Pan, Ban-Zhou, Chen, Jing, De, Wei, Chen, Long-Bang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171617/
https://ncbi.nlm.nih.gov/pubmed/25026294
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