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Expression level of dihydropyrimidine dehydrogenase is associated with clinical outcome in patients with T1G3 bladder cancer treated with Bacillus Calmette-Guerin

BACKGROUND: Recently, it has been shown that 5-fluorouracil (5-FU) with a strong dihydropyrimidine dehydrogenase (DPD) inhibitor elicits a significant response in bladder cancer with a high level of DPD. However, only a few studies investigated the association between the level of the enzyme that re...

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Autores principales: Ide, Hiroki, Kikuchi, Eiji, Mikami, Shuji, Miyajima, Akira, Oya, Mototsugu
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169840/
https://ncbi.nlm.nih.gov/pubmed/25218240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-646
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