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Understanding Molecular Recognition of Promiscuity of Thermophilic Methionine Adenosyltransferase, sMAT from Sulfolobus solfataricus

Methionine adenosyltransferase (MAT) is a family of enzymes that utilizes ATP and methionine to produce S-adenosylmethionine (AdoMet), the most crucial methyl donor in the biological methylation of biomolecules and bioactive natural products. Here, we report that the MAT from Sulfolobus solfataricus...

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Bibliographic Details
Main Authors: Wang, Fengbin, Singh, Shanteri, Zhang, Jianjun, Huber, Tyler D., Helmich, Kate E., Sunkara, Manjula, Hurley, Katherine A., Goff, Randal D., Bingman, Craig A., Morris, Andrew J., Thorson, Jon S., Phillips, George N.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169312/
https://ncbi.nlm.nih.gov/pubmed/24649856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12784
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