Safety and Efficacy of Subretinal Readministration of a Viral Vector in Large Animals to Treat Congenital Blindness

Leber’s congenital amaurosis (LCA) is a group of severe inherited retinal degenerations that are symptomatic in infancy and lead to total blindness in adulthood. Recent clinical trials using recombinant adeno-associated virus serotype 2 (rAAV2) successfully reversed blindness in patients with LCA ca...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Amado, Defne, Mingozzi, Federico, Hui, Daniel, Bennicelli, Jeannette L., Wei, Zhangyong, Chen, Yifeng, Bote, Erin, Grant, Rebecca L., Golden, Jeffrey A., Narfstrom, Kristina, Syed, Nasreen A., Orlin, Stephen E., High, Katherine A., Maguire, Albert M., Bennett, Jean
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169124/
https://ncbi.nlm.nih.gov/pubmed/20374996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000659
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares