Protection of a Single Dose West Nile Virus Recombinant Subviral Particle Vaccine against Lineage 1 or 2 Strains and Analysis of the Cross-Reactivity with Usutu Virus

West Nile virus (WNV) is a neurovirulent mosquito-borne flavivirus. High WNV virulence was mainly associated with lineage 1 strains, but recent outbreaks have unveiled circulation of highly virulent lineage 2 strains. Co-expression of flavivirus prM and E glycoproteins drives the assembly of recombi...

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Bibliographic Details
Main Authors: Merino-Ramos, Teresa, Blázquez, Ana-Belén, Escribano-Romero, Estela, Cañas-Arranz, Rodrigo, Sobrino, Francisco, Saiz, Juan-Carlos, Martín-Acebes, Miguel A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168257/
https://ncbi.nlm.nih.gov/pubmed/25229345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108056
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