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EZH2–miR-30d–KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis

Malignant peripheral nerve sheath tumours (MPNSTs), which develop sporadically or from neurofibromatosis, recur frequently with high metastatic potential and poor outcome. The polycomb group protein enhancer of zeste homologue 2 (EZH2) is an important regulator for various human malignancies. Howeve...

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Detalhes bibliográficos
Main Authors: Zhang, Pingyu, Garnett, Jeannine, Creighton, Chad J, Sannaa, Ghadah Abbas Al, Igram, Davis R, Laza, Alexander, Liu, Xiuping, Liu, Changgong, Pollock, Raphael E
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166508/
https://ncbi.nlm.nih.gov/pubmed/24132643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4294
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