Exploration of Potential Roles of a New LOXL2 Splicing Variant Using Network Knowledge in Esophageal Squamous Cell Carcinoma

LOXL2 (lysyl oxidase-like 2), an enzyme that catalyzes oxidative deamination of lysine residue, is upregulated in esophageal squamous cell carcinoma (ESCC). A LOXL2 splice variant LOXL2-e13 and its wild type were overexpressed in ESCC cells followed by microarray analyses. In this study, we explored...

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Autores principales: Wu, Bing-Li, Lv, Guo-Qing, Zou, Hai-Ying, Du, Ze-Peng, Wu, Jian-Yi, Zhang, Pi-Xian, Xu, Li-Yan, Li, En-Min
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165399/
https://ncbi.nlm.nih.gov/pubmed/25254241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/431792
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