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DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis

Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been implicated in IBD pathology. However, mucosal DNA...

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Bibliographic Details
Main Authors: Harris, R Alan, Nagy-Szakal, Dorottya, Mir, Sabina AV, Frank, Eibe, Szigeti, Reka, Kaplan, Jess L, Bronsky, Jiri, Opekun, Antone, Ferry, George D, Winter, Harland, Kellermayer, Richard
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164498/
https://ncbi.nlm.nih.gov/pubmed/24937444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29446
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