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Destabilization of Akt Promotes the Death of Myeloma Cell Lines
Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the c...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Publishing Corporation
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163362/ https://ncbi.nlm.nih.gov/pubmed/25243120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/190629 |
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