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Destabilization of Akt Promotes the Death of Myeloma Cell Lines
Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the c...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi Publishing Corporation
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163362/ https://ncbi.nlm.nih.gov/pubmed/25243120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/190629 |
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