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Cordon Bleu serves as a platform at the basal region of microvilli, where it regulates microvillar length through its WH2 domains

Cordon Bleu (Cobl) is a WH2-containing protein believed to act as an actin nucleator. We show that it has a very specific localization in epithelial cells at the basal region of microvilli, a localization unlikely to be involved in actin nucleation. The protein is localized by a central region betwe...

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Bibliographic Details
Main Authors: Wayt, Jessica, Bretscher, Anthony
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161516/
https://ncbi.nlm.nih.gov/pubmed/25031432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1131
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