Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures

OBJECTIVE: The role for interferon (IFN)-α in systemic lupus erythematosus (SLE) pathogenesis is strongly supported by gene expression studies. The aim of this study was to improve characterization of the blood-IFN signature in adult SLE patients. METHODS: Consecutive patients were enrolled and foll...

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Main Authors: Chiche, Laurent, Jourde-Chiche, Noémie, Whalen, Elizabeth, Presnell, Scott, Gersuk, Vivian, Dang, Kristen, Anguiano, Esperanza, Quinn, Charlie, Burtey, Stéphane, Berland, Yvon, Kaplanski, Gilles, Harle, Jean-Robert, Pascual, Virginia, Chaussabel, Damien
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157826/
https://ncbi.nlm.nih.gov/pubmed/24644022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38628
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