Testing Two Different Doses of Tiotropium Respimat® in Cystic Fibrosis: Phase 2 Randomized Trial Results

BACKGROUND: Tiotropium is a once-daily, long-acting anticholinergic bronchodilator with the potential to alleviate airway obstruction in cystic fibrosis. Our objective was to evaluate the efficacy and safety of 2.5 and 5 µg once-daily tiotropium delivered via the Respimat Soft Mist Inhaler vs. place...

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Bibliographic Details
Main Authors: Bradley, Judy M., Koker, Paul, Deng, Qiqi, Moroni-Zentgraf, Petra, Ratjen, Felix, Geller, David E., Elborn, J. Stuart
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154718/
https://ncbi.nlm.nih.gov/pubmed/25188297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106195
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