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Differential Binding of Tenofovir and Adefovir to Reverse Transcriptase of Hepatitis B Virus
INTRODUCTION: Resistance of the reverse transcriptase (RT) of hepatitis B virus (HBV) to the tenofovir nucleotide drug has not been observed since its introduction for treatment of hepatitis B virus (HBV) infection in 2008. In contrast, frequent viral breakthrough and resistance has been documented...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4152281/ https://ncbi.nlm.nih.gov/pubmed/25180507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106324 |
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