Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)

Organic anion transporter 3 (OAT3, SLC22A8), a transporter expressed on the basolateral membrane of the proximal tubule, plays a critical role in the renal excretion of organic anions including many therapeutic drugs. The goal of this study was to evaluate the in vivo effects of the OAT3-Ile305Phe v...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Yee, Sook Wah, Nguyen, Anh Nguyet, Brown, Chaline, Savic, Radojka M., Zhang, Youcai, Castro, Richard A., Cropp, Cheryl D., Choi, Ji Ha, Singh, Diment, Tahara, Harunobu, Stocker, Sophie L., Huang, Yong, Brett, Claire M., Giacomini, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151246/
https://ncbi.nlm.nih.gov/pubmed/23649425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23581
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars