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Therapeutic administration of orlistat, rosiglitazone or the chemokine receptor antagonist RS102895 fails to improve the severity of acute pancreatitis in obese mice
OBJECTIVES: Currently there is no therapy for severe acute pancreatitis except for supportive care. The lipase inhibitor orlistat, the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone, and chemokine receptor-2 antagonists attenuate the severity of acute pancreatitis in rodents...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151050/ https://ncbi.nlm.nih.gov/pubmed/24632545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000115 |
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