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Coupling of G Proteins to Reconstituted Monomers and Tetramers of the M(2) Muscarinic Receptor
G protein-coupled receptors can be reconstituted as monomers in nanodiscs and as tetramers in liposomes. When reconstituted with G proteins, both forms enable an allosteric interaction between agonists and guanylyl nucleotides. Both forms, therefore, are candidates for the complex that controls sign...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148863/ https://ncbi.nlm.nih.gov/pubmed/25023280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559294 |
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