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N-glycosylation site occupancy in human prostaglandin H synthases expressed in Pichia pastoris

Prostaglandin H synthases (PGHSs) are N-glycosylated membrane proteins that catalyse the committed step in prostaglandin synthesis. Unlike PGHS-2, the production of recombinant PGHS-1 in non-mammalian expression systems is complicated. The majority of the heterologous enzyme is inactive due to misfo...

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Hlavní autoři: Kukk, Kaia, Kasvandik, Sergo, Samel, Nigulas
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147080/
https://ncbi.nlm.nih.gov/pubmed/25170432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-436
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