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ProSAAS-Derived Peptides Are Differentially Processed and Sorted in Mouse Brain and AtT-20 Cells

ProSAAS is the precursor for some of the most abundant peptides found in mouse brain and other tissues, including peptides named SAAS, PEN, and LEN. Both SAAS and LEN are found in big and little forms due to differential processing. Initial processing of proSAAS is mediated by furin (and/or furin-li...

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Bibliografiske detaljer
Main Authors: Wardman, Jonathan H., Fricker, Lloyd D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141687/
https://ncbi.nlm.nih.gov/pubmed/25148519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104232
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