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Understanding decreased fertility in women carriers of the FMR1 premutation: a possible mechanism for Fragile X-Associated Primary Ovarian Insufficiency (FXPOI)
Fragile X syndrome (FXS) and its associated disorders are caused by the expansion of the CGG repeat in the 5′ untranslated region of the fragile X mental retardation 1 gene (FMR1). The full mutation, defined as >200 cytosine-guanine-guanine (CGG) triplet repeats, causes FXS. Individuals with 55–1...
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| Natura: | Artigo |
| Lingua: | Inglês |
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BioMed Central
2014
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141264/ https://ncbi.nlm.nih.gov/pubmed/25134882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4755-11-67 |
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