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Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to Interferon-α (IFN) in newly diagnosed chronic myeloid leukemia (CML)
The majority of chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) remain with residual disease. In contrast to TKIs, interferon (IFN) is directly toxic to CML progenitor cells, and myeloid growth factors such as GM-CSF may enhance IFN’s cytotoxicity. We performed...
Kaydedildi:
Asıl Yazarlar: | , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2014
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135379/ https://ncbi.nlm.nih.gov/pubmed/25012565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2014.05.012 |
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