Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model

Fibroblast activation protein (FAP) is a specific serine protease expressed in tumor stroma proven to be a stimulatory factor in the progression of some cancers. The purpose of this study was to investigate the effects of FAP knockdown on tumor growth and the tumor microenvironment. Mice bearing 4T1...

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Detalhes bibliográficos
Main Authors: Cai, Fan, Li, Zhiyong, Wang, Chunting, Xian, Shuang, Xu, Guangchao, Peng, Feng, Wei, Yuquan, Lu, You
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133897/
https://ncbi.nlm.nih.gov/pubmed/23710635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.5.172
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