MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production

MicroRNAs have been shown to contribute to a repertoire of host-pathogen interactions during viral infection. Our previous study demonstrated that microRNA-30e* (miR-30e*) directly targeted the IκBα 3′-UTR and disrupted the NF-κB/IκBα negative feedback loop, leading to hyperactivation of NF-κB. This...

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Detalhes bibliográficos
Main Authors: Zhu, Xun, He, Zhenjian, Hu, Yiwen, Wen, Weitao, Lin, Cuiji, Yu, Jianchen, Pan, Jing, Li, Ran, Deng, Haijing, Liao, Shaowei, Yuan, Jie, Wu, Jueheng, Li, Jun, Li, Mengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133224/
https://ncbi.nlm.nih.gov/pubmed/25122182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003088
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