A data-driven model of biomarker changes in sporadic Alzheimer's disease

We demonstrate the use of a probabilistic generative model to explore the biomarker changes occurring as Alzheimer’s disease develops and progresses. We enhanced the recently introduced event-based model for use with a multi-modal sporadic disease data set. This allows us to determine the sequence i...

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Bibliographic Details
Main Authors: Young, Alexandra L., Oxtoby, Neil P., Daga, Pankaj, Cash, David M., Fox, Nick C., Ourselin, Sebastien, Schott, Jonathan M., Alexander, Daniel C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132648/
https://ncbi.nlm.nih.gov/pubmed/25012224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu176
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