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Regulation and Role of EZH2 in Cancer

Polycomb repressive complex 2 (PRC2) is the epigenetic regulator that induces histone H3 lysine 27 methylation (H3K27me3) and silences specific gene transcription. Enhancer of zeste homolog 2 (EZH2) is an enzymatic subunit of PRC2, and evidence shows that EZH2 plays an essential role in cancer initi...

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Main Authors: Yamaguchi, Hirohito, Hung, Mien-Chie
格式: Artigo
語言:Inglês
出版: Korean Cancer Association 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132442/
https://ncbi.nlm.nih.gov/pubmed/25038756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2014.46.3.209
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